Michael G. Fried, PhD
About
Faculty Rank
- Professor
Research
Research Focus
DNA repair, mutagenesis, chemotherapy.
Programs
Molecular and Cellular OncologyCollege & Department
Contact Information
259-B BBSRB
741 S. Limestone, University of Kentucky
Lexington, KY 40502
United States
Phone
Email
Publications
- Equilibria and Kinetics of Lac Repressor-Operator Interactions by Polyacrylamide Gel Electrophoresis.Fried MG and Crothers DM. Nucl Acids Re. 9:6505-6525, 1981.
- DNA Looping and Lac Repressor-CAP Interaction.Fried MG and Hudson JM. Science 274:1930-1931, 1996.
- Flipping of alkylated DNA damage bridges base and nucleotide excision repair.Tubbs JL, Butt S, Kanugula M, Melikishvili M, Marriott A, Watson AJ, Verbeek B, Santibanez-Koref MF, Kraehenbuehl R, Fleck O, Millington C, Arvai AS, Kroeger MD, Peterson LA, Williams DM, Fried MG, Margison GP, Pegg AE and Tainer JA. Nature 459:808-813, 2009.
- Topologies Of Complexes Containing O6-Alkylguanine-DNA-Alkyltransferase And DNA.Adams CA, Melikishvili M, Rodgers DW, Rasimas JJ, Pegg AE and Fried MG. Journal of Molecular Biology, 389:248-263, 2009.
- Mutations That Probe The Cooperative Assembly Of O6-Alkylguanine-DNA Alkyltransferase (AGT) Complexes.Adams CA and Fried MG. Biochemistry 50:1590-1598, 2011.