Qiou Wei, PhD

About

Redox biology, cancer biology, tumorigenesis and cancer progression.

1095 VA Drive
140 HSRB, University of Kentucky
Lexington, KY 40536
United States

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Loss of Sulfiredoxin renders mice resistance to AOM/DSS induced colon carcinogenesis.
Wei Q, Jiang H, Baker A, Dodge LK, Gerard M, Young MR, Toledano MB, Colburn NH. 2013. Carcinogenesis 34(6):1403-10, 2013.
The Srx-PrxIV axis promotes human lung cancer progression through modulation of specific phosphokinase signaling pathways.
Wei Q, Jiang H, Xiao Z, Baker A, Young MR, Veenstra TD, Colburn NH. Proc Natl Acad Sci USA 108(17):7004-9, 2011.
Sulfiredoxin is an AP-1 target gene that is required for transformation and shows elevated expression in human skin malignancies.
Wei Q, Jiang H, Matthews CP, Colburn NH. Proc Natl Acad Sci USA 105(50):19738-19743, 2008.
R-spondin1 is a high affinity ligand for LRP6 and induces phosphorylation of LRP6 and activation of the b-catenin pathway.
Wei Q, Yokota C, Semenov MV, Doble B, Woodgett J, He X. J Biol Chem 282(21):15903-15911, 2007.
The Sp1 family of transcription factors is involved in p27(Kip1)-mediated activation of myelin basic protein gene expression.
Wei Q, Miskimins WK, Miskimins R. Mol. Cell Biol. 23(12):4035-4045, 2003.